COVID-BRain Advanced Imaging Network
HELP US UNDERSTAND LONG-COVID
This study aims to understand the long-term impact of COVID-19 on the brain through imaging. This is a multi-site study led by University of Minnesota, Mayo Clinic Rochester, and Harvard University and is supported by the National Institutes of Health (NIH).
Why is this study important?
Many people who have had COVID-19 are reporting symptoms for weeks to months, even after they recover from their initial illness. To be able to overcome long-COVID we need to learn more about what kinds of changes are happening in the brains of people recovering from COVID-19.
COVID-19 is affecting underserved communities the most. Therefore, we invite communities most impacted to join forces with us in this study. By understanding the causes of these long-lasting symptoms, we can treat them better.
Who can join?
We are looking for individuals who had COVID-19 and are still having symptoms like headaches, “brain fog”, feeling tired, dizziness, memory problems, or loss of taste or smell. We especially need patients who were hospitalized with COVID-19.
We are also looking for individuals who did not have COVID-19.
Learn more about the study
Basic Eligibility Criteria
- At least 18 years of age
- Individuals who had laboratory confirmed COVID-19 or no known COVID-19 exposure (healthy control volunteers)
- Ongoing symptoms such as headaches, brain fog, memory problems if you had COVID-19
- Able to undergo MR scanning
- English or Spanish speaking
What happens if I agree to participate in this study?
If you agree to participate in this study, we will ask you to come to the study center for the following:
- Medical history collection
- Physical examination
- MRI scan (What is it like to get an MRI?) – the scan does not include contrast or any tasks in scanner
- Blood draw (What is it like to have a blood test?)
- Cognitive (e.g. memory, reasoning, attention) testing
- Study questionnaires
We will reach out to you every three months while you are in this study to check in on your symptoms and see if you have any questions. We may invite you for a second visit about two years after the first visit.
Is there compensation for study participants?
Yes, we will compensate you for each completed study visit. You will not be responsible for the cost of any study procedure. Public transportation fees or parking will be additionally provided. If you need to stop study procedures for any reason, you will receive partial payment for your time.
Who is conducting this study?
University of Minnesota:
Study Lead: Gülin Öz, PhD
Study Coordinator: Katie Gundry
Mayo Clinic Rochester:
Study Lead: Kejal Kantarci, MD
Study Coordinator: June C. Kendall Thomas
Massachusettes General Hospital/Harvard University:
Study Lead: Eva Ratai, PhD
Study Coordinator: Ellie Enichen
Houston Methodist Research Institute:
Study Lead: Tetsuo Ashizawa, MD
Study Coordinator: Titilayo Olubajo
Johns Hopkins University:
Study Lead: Peter Barker, PhD